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Breakthrough treatment proves 90 success rate on painful anal fissures. Most anal fissures will heal with treatment, although they can happen again easily, particularly if you dont follow the self-help advice outlined below. There are a number of self-help measures your gp may recommend to relieve constipation and reduce the pain caused by anal fissures. In approximately 90 of patients the anal fissure is located in the posterior midline. It is hypothesised that this predilection for the posterior midline may occur because this portion of the anal canal is poorly perfused. 7, 8 anterior anal fissures affect approximately 10 of patients and may have a different pathophysiology. They are associated with younger, mostly female, patients often. 2) in the treatment of anal fissures researchers concluded that, in general, the effects of anti-fisher difference between lidocaine ointment and cream there is significant, but given the nature of the compounds used in anti-fisher cream and the possibility of producing it inside the country should pay special attention to these products, the medical treatment of anal fissure. I have anal fissure can i use triple antibiotic ointment on it or i have nitro ointment they gave me for when i. Nitro ointment would be a better choice than antibiotic ointment as it relaxes your sphincter muscle thus relieving pain due to fissure,easy defaecation. The treatment of anal fistulas, especially if the patient presents with systemic symptoms. Postoperative prophylactic antibiotic therapy for 7-10 days (eg. Clove oil cream a new effective treatment for chronic anal fissure.). acute anal fissures -- the ones that dont last longer than 6 weeks -- are common and usually heal on their own with self-care. Probably won&x27t help antibiotics don&x27t usually help anal fissures or speed healing. Main treatments are vasodilating ointments (nitroglycerine, nifedipine) and fiber products etc to avoid constipation and keep stools soft. Breakthrough treatment proves 90 success rate on painful anal fissures.