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What is the real cause of chronic anal itch and which remedy proves to be best. Twenty percent or more of people may have a rash after surgery. Post-surgical rash may be caused by drugs or exposure to substances used before, during, or after surgery. I had anal pain thats why doctor give me lignox 2 there is any side effects for me when i apply at anal side. Before that i have anal fissur plz guide me about now this is work or any side effect plz. Topical anesthetics are medicines that numb and reduce the sensation of pain in the area to which they are applied. They are available as creams, ointments, solutions, eye drops, gels or sprays and may be applied to areas such as the skin, inside the mouth or throat, in the nose, or in the eyes. Lidocaine 3 cream is a topical anesthetic indicated for the relief of pruritus, pruritic eczemas, abrasions, minor burns, insect bites, pain, soreness, and discomfort due to pruritus ani, pruritus vulvae, hemorrhoids, anal fissures, and similar conditions of the skin and mucous membranes. You probably didnt learn how to prepare for anal sex in sex edand unlike p-in-v (or toy-in-v) sex, anal play does require some planning ahead. Looking for medication to treat itching? Find a list of current medications, their possible side effects, dosage, and efficacy when used to treat or reduce the symptoms of itching. Histamine is released from mast cells when tissues are inflamed or stimulated by allergens 11,12, and once released, histamine induces itch is triggered by the excitation of a subset of unmyelinated c-fibers. Histamine receptors are known to mediate histamine-induced responses, and are members of the g-protein-coupled receptors. What is the real cause of chronic anal itch and which remedy proves to be best.