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Cytology (anal pap) negative or normal-when the pathologist examined the cells from the pap smear under a microscope, she found no abnormal cells or signs of hpv-related changesanal cytology is a fairly good indicator of who should be examined and who might have hsil, but it is not the best way to determine the severity of sil nor is it the best way to diagnose invasive anal cancer. An anal pap smear is performed to screen for anal hsil in the following manner. Should not be used prior to obtaining a cytology sample because the lubricant may interfere with the processing and interpretation of the sample. evaluation of anal-rectal cytology is similar to that of cervical pap tests. The diagnosis of anal dysplasia may be made by performing an anal pap smear. Just like a cervical pap smear, cells are collected from a swab inserted into the anus. Those cells are then examined by a pathologist looking for pre-cancerous or dysplastic changes. Malefemale patients with any of the following risk factors should have an anal pap. Anal pap smears (cytology) a small swab is passed just inside the anus to collect cells, which are suspended in fluid, stained and examined under a microscope. They are graded from least to more likely to flag pre-cancerous changes negative (no abnormal cells), ascus (atypical squamous cells of undetermined significance), lsil (low-grade squamous intraepithelial lesion) and hsil (the same.). Burden and implications of hpv-related anal disease in individuals with hiv. Medical care criteria committee, with gina brown, md, march 2020. The american cancer society estimates 8,300 new cases of anal cancer for 2019 in the general population 2,770 in men and 5,530 in women acs 2019. Cervical and vaginal cytology interpretation of results (pap test report) view in chinese. Anal cancer with anal papanicolaou (pap) smears is controversial, we agree with the infectious disease society of america guidelines, which recommend anal pap tests for hiv-positive msm,. the only cpt codes specifically for pap smears are for use by a pathologist, for the interpretation of the cytology specimen. Cpt codes in the lab section, 88000 series, should not be reported by the office physician who collects the pap smear. Those codes are used by the pathologist who provides the interpretation of the pap smear. Anal cytology was first included in the 2001 bethesda atlas and has gained acceptance as a tool for anal cancer screening in conjunction with high-resolution anoscopy and biopsy - in a role similar to that of the pap test. This edition further elaborates on new epidemiologic literature and defines high-risk populations. Anal pap smear screening involves inserting a swab blindly into the anal canal and fixing the cells either on a slide or in fluid for liquid cytological examination. 92 between each pathologist and the consensus interpretation of all 4 pathologists.