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lidocaine and benzocaine are both medications that are used as local anesthetics. They share structural similarities, and have similar means of acting on the human body, but they also have important differences. These drugs have somewhat different anesthetic and chemical properties, which determine how appropriate they are for use in different medical situations. Lidocaine 2 jelly safe for anal sex kmama2131 a few years ago my mom was diagnosed with vaginal and rectal cancer in the end the doctor prescribed her lidocaine 2 jelly for painful intercourse and bowel movements. lidocaine 3 cream is a topical anesthetic indicated for the relief of pruritus, pruritic eczemas, abrasions, minor burns, insect bites, pain, soreness, and discomfort due to pruritus ani, pruritus vulvae, hemorrhoids, anal fissures, and similar conditions of the skin and mucous membranes. If you feel any pain or notice bleeding after anal sex, this could be a sign of some internal damage. Sex is meant to be enjoyable, so find what lights your fire and stoke it. But, if anal penetration doesnt do it for you, experiment to find out what does! As an alternative to using numbing lube, try other options to make anal sex more. benzocaine lube burns when used anally? Me and my girlfriend are experimenting with anal sex. We tried to use adam and eve analeasy, which is a benzocaine 7. After a while she goes numb, but then touching that area at all makes it burn again.