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Anal cancer is an uncommon malignancy that starts in the anus-- the opening at the end of the rectum. The american society of clinical oncology estimates that 8,300 cases of anal cancer will be. At first, most people assume the bleeding is caused by hemorrhoids (painful, swollen veins in the anus and rectum that may bleed). They are a benign and fairly common cause of rectal bleeding. Sometimes abnormal cells on the inner surface layer of the anus look like cancer cells but have not grown into any of the deeper layers. This is known as carcinoma in situ, (pronounced in sy-too), or cis. Anal cancer is a rare form of cancer that affects the tissues of the anus. We explain what you need to know about its causes and how its diagnosed. Anal cancer is a cancer which arises from the anus, the distal opening of the gastrointestinal tract. Symptoms may include bleeding from the anus or a lump near the anus. Other symptoms may include pain, itchiness, or discharge from the anus. anal cancer cases have been increasing over several decades. Infection with human papillomavirus (hpv) is the major risk factor for anal cancer. Start here to find information on anal cancer treatment, causes and prevention, research, and statistics. Anal cancer treatment options include radiation therapy, chemotherapy, andor surgery. Get detailed information about newly diagnosed and recurrent anal cancer including risk factors, symptoms, diagnosis, prognosis, and treatment in this expert-reviewed summary. It is a rare cancer, more commonly diagnosed in people aged 50 to 60 years. Anal cancer is a rare disease, affecting over 1,400 people a year in the uk. The anus (back passage) is the 4cm long end portion of the large bowel, which opens to allow solid waste to exit the body.